Recombinant domains III of Tick-Borne Encephalitis Virus envelope protein in combination with dextran and CpGs induce immune response and partial protectiveness against TBE virus infection in mice

BACKGROUND: E protein of tick-borne encephalitis virus (TBEV) and other flaviviruses is located on the surface of the viral particle. Domain III of this protein seems to be a promising component of subunit vaccines for prophylaxis of TBE and kits for diagnostics of TBEV. METHODS: Three variants of r...

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Detalles Bibliográficos
Autores principales: Ershova, Anna S., Gra, Olga A., Lyaschuk, Alexander M., Grunina, Tatyana M., Tkachuk, Artem P., Bartov, Mikhail S., Savina, Darya M., Sergienko, Olga V., Galushkina, Zoya M., Gudov, Vladimir P., Kozlovskaya, Liubov I., Kholodilov, Ivan S., Gmyl, Larissa V., Karganova, Galina G., Lunin, Vladimir G., Karyagina, Anna S., Gintsburg, Alexander L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054610/
https://www.ncbi.nlm.nih.gov/pubmed/27717318
http://dx.doi.org/10.1186/s12879-016-1884-5

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