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Effects of Melanocortin 3 and 4 Receptor Deficiency on Energy Homeostasis in Rats

Melanocortin-3 and 4 receptors (MC3R and MC4R) can regulate energy homeostasis, but their respective roles especially the functions of MC3R need more exploration. Here Mc3r and Mc4r single and double knockout (DKO) rats were generated using CRISPR-Cas9 system. Metabolic phenotypes were examined and...

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Detalles Bibliográficos
Autores principales:	You, Panpan, Hu, Handan, Chen, Yuting, Zhao, Yongliang, Yang, Yiqing, Wang, Tongtong, Xing, Roumei, Shao, Yanjiao, Zhang, Wen, Li, Dali, Chen, Huaqing, Liu, Mingyao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054679/ https://www.ncbi.nlm.nih.gov/pubmed/27713523 http://dx.doi.org/10.1038/srep34938

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