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The Role of IRE-XBP1 Pathway in Regulation of Retinal Pigment Epithelium Tight Junctions
PURPOSE: The retinal pigment epithelium (RPE) tight junctions play a pivotal role in maintaining the homeostatic environment of the neural retina. Herein, we investigated the role of X-box binding protein 1 (XBP1), an endoplasmic reticulum (ER) stress-responsive transcription factor, in regulation o...
Autores principales: | Ma, Jacey H., Wang, Joshua J., Li, Junhua, Pfeffer, Bruce A., Zhong, Yiming, Zhang, Sarah X. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Association for Research in Vision and Ophthalmology
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054729/ https://www.ncbi.nlm.nih.gov/pubmed/27701635 http://dx.doi.org/10.1167/iovs.16-19232 |
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