Promise of cancer stem cell vaccine

Dendritic cell (DC)-based vaccines designed to target cancer stem cells (CSC) can induce significant antitumor responses via conferring host anti-CSC immunity. Our recent studies have demonstrated that CSC-DC vaccine could inhibit metastasis of primary tumors and induce humoral immune responses agai...

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Detalles Bibliográficos
Autores principales: Zhou, Li, Lu, Lin, Wicha, Max S, Chang, Alfred E, Xia, Jian-chuan, Ren, Xiubao, Li, Qiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Commentaries
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054775/
https://www.ncbi.nlm.nih.gov/pubmed/26337078
http://dx.doi.org/10.1080/21645515.2015.1083661
Descripción
Sumario:Dendritic cell (DC)-based vaccines designed to target cancer stem cells (CSC) can induce significant antitumor responses via conferring host anti-CSC immunity. Our recent studies have demonstrated that CSC-DC vaccine could inhibit metastasis of primary tumors and induce humoral immune responses against cancer stem cells. This approach highlights the promise of cancer stem cell vaccine in cancer immunotherapy.

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