A limit to the divergent allele advantage model supported by variable pathogen recognition across HLA‐DRB1 allele lineages

Genetic diversity in human leukocyte antigen (HLA) molecules is thought to have arisen from the co‐evolution between host and pathogen and maintained by balancing selection. Heterozygote advantage is a common proposed scenario for maintaining high levels of diversity in HLA genes, and extending from...

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Detalles Bibliográficos
Autores principales: Lau, Q., Yasukochi, Y., Satta, Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054888/
https://www.ncbi.nlm.nih.gov/pubmed/26392055
http://dx.doi.org/10.1111/tan.12667

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054888/
https://www.ncbi.nlm.nih.gov/pubmed/26392055
http://dx.doi.org/10.1111/tan.12667

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