Assessment of first and second degree relatives of individuals with bipolar disorder shows increased genetic risk scores in both affected relatives and young At‐Risk Individuals

Recent studies have revealed the polygenic nature of bipolar disorder (BP), and identified common risk variants associated with illness. However, the role of common polygenic risk in multiplex families has not previously been examined. The present study examined 249 European‐ancestry families from t...

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Detalles Bibliográficos
Autores principales: Fullerton, Janice M., Koller, Daniel L., Edenberg, Howard J., Foroud, Tatiana, Liu, Hai, Glowinski, Anne L., McInnis, Melvin G., Wilcox, Holly C., Frankland, Andrew, Roberts, Gloria, Schofield, Peter R., Mitchell, Philip B., Nurnberger, John I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054905/
https://www.ncbi.nlm.nih.gov/pubmed/26178159
http://dx.doi.org/10.1002/ajmg.b.32344

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