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Association between targeted somatic mutation (TSM) signatures and HGS‐OvCa progression

Evidence already exists that the activation‐induced cytidine deaminase (AID/APOBEC) and the adenosine deaminase (ADAR) families of enzymes are implicated as powerful mutagens in oncogenic processes in many somatic tissues. Each deaminase is identified by the DNA or RNA nucleotide sequence (“motif”)...

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Detalles Bibliográficos
Autores principales:	Lindley, Robyn A., Humbert, Patrick, Larner, Cliff, Akmeemana, Eric H., Pendlebury, Christopher R. R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2016
Materias:	Cancer Prevention
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055158/ https://www.ncbi.nlm.nih.gov/pubmed/27485054 http://dx.doi.org/10.1002/cam4.825

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