Cargando…
Long-Lived CD4(+)IFN-γ(+) T Cells rather than Short-Lived CD4(+)IFN-γ(+)IL-10(+) T Cells Initiate Rapid IL-10 Production To Suppress Anamnestic T Cell Responses during Secondary Malaria Infection
CD4(+) T cells that produce IFN-γ are the source of host-protective IL-10 during primary infection with a number of different pathogens, including Plasmodium spp. The fate of these CD4(+)IFN-γ(+)IL-10(+) T cells following clearance of primary infection and their subsequent influence on the course of...
Autores principales: | Villegas-Mendez, Ana, Inkson, Colette A., Shaw, Tovah N., Strangward, Patrick, Couper, Kevin N. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AAI
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055201/ https://www.ncbi.nlm.nih.gov/pubmed/27630165 http://dx.doi.org/10.4049/jimmunol.1600968 |
Ejemplares similares
-
Parasite-Specific CD4(+) IFN-γ(+) IL-10(+) T Cells Distribute within Both Lymphoid and Nonlymphoid Compartments and Are Controlled Systemically by Interleukin-27 and ICOS during Blood-Stage Malaria Infection
por: Villegas-Mendez, Ana, et al.
Publicado: (2015) -
In Vivo Priming of Cd4 T Cells That Produce Interleukin (Il)-2 but Not IL-4 or Interferon (Ifn)-γ, and Can Subsequently Differentiate into IL-4–Or IFN-γ–Secreting Cells
por: Wang, Xiaowen, et al.
Publicado: (2001) -
IFNγ/IL-10 Co-producing Cells Dominate the CD4 Response to Malaria in Highly Exposed Children
por: Jagannathan, Prasanna, et al.
Publicado: (2014) -
Human IL-21(+)IFN-γ(+)CD4(+) T cells in nasal polyps are regulated by IL-12
por: Xiao, Li, et al.
Publicado: (2015) -
Mycobacterium tuberculosis-Specific IL-21(+)IFN-γ(+)CD4(+) T Cells Are Regulated by IL-12
por: Li, Li, et al.
Publicado: (2016)