Cargando…

Prognostic and therapeutic value of mitochondrial serine hydroxyl-methyltransferase 2 as a breast cancer biomarker

Mitochondrial serine hydroxylmethyltransferase 2 (SHMT2) is a key enzyme in the serine/glycine synthesis pathway. SHMT2 has been implicated as a critical component for tumor cell survival. The aim of the present study was to evaluate the prognostic value and efficiency of SHMT2 as a biomarker in pat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Lahong, Chen, Zhaojun, Xue, Dan, Zhang, Qi, Liu, Xiyong, Luh, Frank, Hong, Liquan, Zhang, Hang, Pan, Feng, Liu, Yuhua, Chu, Peiguo, Zheng, Shu, Lou, Guoqiang, Yen, Yun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2016
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055214/ https://www.ncbi.nlm.nih.gov/pubmed/27666119 http://dx.doi.org/10.3892/or.2016.5112

Ejemplares similares

Overexpression of mitochondrial serine hydroxyl-methyltransferase 2 is associated with poor prognosis and promotes cell proliferation and invasion in gliomas
por: Wu, Ming, et al.
Publicado: (2017)

Detection of plasma exosomal miRNA-205 as a biomarker for early diagnosis and an adjuvant indicator of ovarian cancer staging
por: Zhu, Zehua, et al.
Publicado: (2022)

miR-125b inhibited epithelial–mesenchymal transition of triple-negative breast cancer by targeting MAP2K7
por: Hong, Liquan, et al.
Publicado: (2016)

Prognostic and therapeutic significance of ribonucleotide reductase small subunit M2 in estrogen-negative breast cancers
por: Zhang, Hang, et al.
Publicado: (2014)

Combined Detection of IFN-γ and Lymphocyte Subsets with Activation Indicators in the Clinical Application of Mycobacterium Tuberculosis Infection at Different Times
por: Chen, Yiwen, et al.
Publicado: (2023)

Rapid diagnosis of pulmonary tuberculosis and detection of drug resistance by combined simultaneous amplification testing and reverse dot blot
por: Chen, Yiwen, et al.
Publicado: (2018)

Expression of DNA Translesion Synthesis Polymerase η in Head and Neck Squamous Cell Cancer Predicts Resistance to Gemcitabine and Cisplatin-Based Chemotherapy
por: Zhou, Wendi, et al.
Publicado: (2013)

Ribonucleotide reductase small subunit M2 serves as a prognostic biomarker and predicts poor survival of colorectal cancers
por: Liu, Xiyong, et al.
Publicado: (2013)

The effect of rice husk nanosilica hydroxyl compound on dentin biomineralization
por: Aprillia, Iffi, et al.
Publicado: (2021)

Hemiacetal stabilization in a chymotrypsin inhibitor complex and the reactivity of the hydroxyl group of the catalytic serine residue of chymotrypsin
por: Cleary, Jennifer A., et al.
Publicado: (2014)

Determining the inherent selectivity for carbon radical hydroxylation versus halogenation with high-spin oxoiron(iv)–halide complexes: a concerted rebound step
por: Tao, Yaping, et al.
Publicado: (2022)

Atomically dispersed chromium coordinated with hydroxyl clusters enabling efficient hydrogen oxidation on ruthenium
por: Zhang, Bingxing, et al.
Publicado: (2022)

Diagnostic value of clusterin immunostaining in hepatocellular carcinoma
por: Li, Yuan, et al.
Publicado: (2020)

A biocatalytic hydroxylation-enabled unified approach to C19-hydroxylated steroids
por: Wang, Junlin, et al.
Publicado: (2019)

A constitutive serine protease inhibitor suppresses herbivore performance in tea (Camellia sinensis)
por: Ye, Meng, et al.
Publicado: (2023)

Kinetic study of hydroxyl radical formation in a continuous hydroxyl generation system
por: Wang, Xin, et al.
Publicado: (2018)

Human Mitotic Centromere-Associated Kinesin Is Targeted by MicroRNA 485-5p/181c and Prognosticates Poor Survivability of Breast Cancer
por: Lu, Huajun, et al.
Publicado: (2019)

Methyltransferase G9a promotes cervical cancer angiogenesis and decreases patient survival
por: Chen, Ruey-Jien, et al.
Publicado: (2017)

Overexpression of Uridine-Cytidine Kinase 2 Correlates with Breast Cancer Progression and Poor Prognosis
por: Shen, Guosong, et al.
Publicado: (2017)

Ribonucleotide Reductase Large Subunit M1 Predicts Poor Survival Due to Modulation of Proliferative and Invasive Ability of Gastric Cancer
por: Wang, Qinchuan, et al.
Publicado: (2013)

Roles of Mitochondrial Serine Hydroxymethyltransferase 2 (SHMT2) in Human Carcinogenesis
por: Zeng, Yuanyuan, et al.
Publicado: (2021)

Dihydrofolate reductase, thymidylate synthase, and serine hydroxy methyltransferase: successful targets against some infectious diseases
por: Shamshad, Hina, et al.
Publicado: (2022)

Small RNA-mediated DNA (cytosine-5) methyltransferase 1 inhibition leads to aberrant DNA methylation
por: Zhang, Guoqiang, et al.
Publicado: (2015)

P16-specific DNA methylation by engineered zinc finger methyltransferase inactivates gene transcription and promotes cancer metastasis
por: Cui, Chenghua, et al.
Publicado: (2015)

Serine Availability Influences Mitochondrial Dynamics and Function through Lipid Metabolism
por: Gao, Xia, et al.
Publicado: (2018)

Expression and the Prognostic Value of Biglycan in Gastric Cancer
por: Hu, Sizhe, et al.
Publicado: (2022)

The II–I Phase Transition Behavior of Butene-1 Copolymers with Hydroxyl Groups
por: Li, Yuanyuan, et al.
Publicado: (2021)

Hydroxyl-Directed Stereoselective Diboration of Alkenes
por: Blaisdell, Thomas P., et al.
Publicado: (2014)

Kinesin family member 11 is a potential therapeutic target and is suppressed by microRNA‐30a in breast cancer
por: Wang, Benfang, et al.
Publicado: (2020)

A mitochondrial rRNA dimethyladenosine methyltransferase in Arabidopsis
por: Richter, Uwe, et al.
Publicado: (2010)

Catalytic Hydroxylation of Polyethylenes
por: Bunescu, Ala, et al.
Publicado: (2017)

Serine catabolism is essential to maintain mitochondrial respiration in mammalian cells
por: Lucas, Stephanie, et al.
Publicado: (2018)

The Hydroxyl at Position C1 of Genipin Is the Active Inhibitory Group that Affects Mitochondrial Uncoupling Protein 2 in Panc-1 Cells
por: Yang, Yang, et al.
Publicado: (2016)

The complete mitochondrial genome of Lambis chiragra
por: Liu, Guoqiang, et al.
Publicado: (2020)

A top-down strategy for amorphization of hydroxyl compounds for electrocatalytic oxygen evolution
por: Liu, Shangheng, et al.
Publicado: (2022)

PHD3 inhibits cell proliferation through hydroxylation of PAX2 at proline 9: PHD3 hydroxylates PAX2
por: Lun, Jie, et al.
Publicado: (2022)

The mechanisms and process of acephate degradation by hydroxyl radical and hydrated electron
por: Huang, Yuanyuan, et al.
Publicado: (2018)

Microporous organic hydroxyl-functionalized polybenzotriazole for encouraging CO(2) capture and separation
por: Yin, Qiang, et al.
Publicado: (2019)

Catalytic asymmetric hydroxylative dearomatization of 2-naphthols: synthesis of lacinilene derivatives
por: Zhang, Yu, et al.
Publicado: (2017)

Controlling CNT-Based Nanorotors via Hydroxyl Groups
por: Zhang, Boyang, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_ed9901uns1q6bs1s4efkold8lf