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Differences in Proinflammatory Property of Six Subtypes of Peroxiredoxins and Anti-Inflammatory Effect of Ligustilide in Macrophages

BACKGROUND: Peroxiredoxins (Prxs) are proposed to function as damage-associated molecular patterns (DAMPs) and contribute to post-ischemic neuroinflammation and brain injury by activating Toll-like receptor (TLR) 4 at the acute and subacute phases after ischemic stroke. However, there are few studie...

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Detalles Bibliográficos
Autores principales: Zhao, Li-Xue, Du, Jun-Rong, Zhou, Hong-Jing, Liu, Dong-Ling, Gu, Man-Xia, Long, Fang-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055302/
https://www.ncbi.nlm.nih.gov/pubmed/27716839
http://dx.doi.org/10.1371/journal.pone.0164586