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A High-Throughput Small Molecule Screen for C. elegans Linker Cell Death Inhibitors

Programmed cell death is a ubiquitous process in metazoan development. Apoptosis, one cell death form, has been studied extensively. However, mutations inactivating key mammalian apoptosis regulators do not block most developmental cell culling, suggesting that other cell death pathways are likely i...

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Detalles Bibliográficos
Autores principales: Schwendeman, Andrew R., Shaham, Shai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055323/
https://www.ncbi.nlm.nih.gov/pubmed/27716809
http://dx.doi.org/10.1371/journal.pone.0164595