Thioredoxin Inhibitors Attenuate Platelet Function and Thrombus Formation

Thioredoxin (Trx) is an oxidoreductase with important physiological function. Imbalances in the NADPH/thioredoxin reductase/thioredoxin system are associated with a number of pathologies, particularly cancer, and a number of clinical trials for thioredoxin and thioredoxin reductase inhibitors have b...

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Detalles Bibliográficos
Autores principales: Metcalfe, Clive, Ramasubramoni, Anjana, Pula, Giordano, Harper, Matthew T., Mundell, Stuart J., Coxon, Carmen H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055343/
https://www.ncbi.nlm.nih.gov/pubmed/27716777
http://dx.doi.org/10.1371/journal.pone.0163006

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