Low Levels of NDRG1 in Nerve Tissue Are Predictive of Severe Paclitaxel-Induced Neuropathy

INTRODUCTION: Sensory peripheral neuropathy caused by paclitaxel is a common and dose limiting toxicity, for which there are currently no validated predictive biomarkers. We investigated the relationship between the Charcot-Marie-Tooth protein NDRG1 and paclitaxel-induced neuropathy. METHODS/MATERIA...

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Detalles Bibliográficos
Autores principales: Sundar, Raghav, Jeyasekharan, Anand D., Pang, Brendan, Soong, Richie Chuan Teck, Kumarakulasinghe, Nesaretnam Barr, Ow, Samuel Guan Wei, Ho, Jingshan, Lim, Joline Si Jing, Tan, David Shao Peng, Wilder-Smith, Einar P. V., Bandla, Aishwarya, Tan, Stacey Sze Hui, Asuncion, Bernadette Reyna, Fazreen, Zul, Hoppe, Michal Marek, Putti, Thomas Choudary, Poh, Lay Mui, Goh, Boon Cher, Lee, Soo-Chin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055363/
https://www.ncbi.nlm.nih.gov/pubmed/27716814
http://dx.doi.org/10.1371/journal.pone.0164319

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