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Plate-based diversity subset screening generation 2: an improved paradigm for high-throughput screening of large compound files
High-throughput screening (HTS) is an effective method for lead and probe discovery that is widely used in industry and academia to identify novel chemical matter and to initiate the drug discovery process. However, HTS can be time consuming and costly and the use of subsets as an efficient alternat...
Autores principales: | Bell, Andrew S., Bradley, Joseph, Everett, Jeremy R., Loesel, Jens, McLoughlin, David, Mills, James, Peakman, Marie-Claire, Sharp, Robert E., Williams, Christine, Zhu, Hongyao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055576/ https://www.ncbi.nlm.nih.gov/pubmed/27631533 http://dx.doi.org/10.1007/s11030-016-9692-9 |
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