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Rapid and efficient generation of neural progenitors from adult bone marrow stromal cells by hypoxic preconditioning

BACKGROUND: Bone marrow stromal cells (BMSCs) are attractive as a source of neural progenitors for ex vivo generation of neurons and glia. Limited numbers of this subpopulation, however, hinder translation into autologous cell-based therapy. Here, we demonstrate rapid and efficient conditioning with...

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Detalles Bibliográficos
Autores principales: Mung, Kwan-Long, Tsui, Yat-Ping, Tai, Evelyn Wing-Yin, Chan, Ying-Shing, Shum, Daisy Kwok-Yan, Shea, Graham Ka-Hon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055711/
https://www.ncbi.nlm.nih.gov/pubmed/27717376
http://dx.doi.org/10.1186/s13287-016-0409-x