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Characterisation of colonic dysplasia-like epithelial atypia in murine colitis

AIM: To determine if exacerbation of pre-existing chronic colitis in Winnie (Muc2 mutant) mice induces colonic dysplasia. METHODS: Winnie mice and C57BL6 as a genotype control, were administered 1% w/v dextran sulphate sodium (DSS) orally, followed by drinking water alone in week-long cycles for a t...

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Detalles Bibliográficos
Autores principales: Randall-Demllo, Sarron, Fernando, Ruchira, Brain, Terry, Sohal, Sukhwinder Singh, Cook, Anthony L, Guven, Nuri, Kunde, Dale, Spring, Kevin, Eri, Rajaraman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055864/
https://www.ncbi.nlm.nih.gov/pubmed/27729740
http://dx.doi.org/10.3748/wjg.v22.i37.8334