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Response of Mouse Zygotes Treated with Mild Hydrogen Peroxide as a Model to Reveal Novel Mechanisms of Oxidative Stress-Induced Injury in Early Embryos

Our study aimed to develop embryo models to evaluate the impact of oxidative stress on embryo development. Mouse zygotes, which stayed at G1 phase, were treated with prepared culture medium (containing 0.00, 0.01, 0.02, 0.03, 0.04, 0.05, or 0.1 mM hydrogen peroxide (H(2)O(2))) for 30 min in experime...

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Detalles Bibliográficos
Autores principales: Qian, Diting, Li, Zhiling, Zhang, Yuting, Huang, Yue, Wu, Que, Ru, Gaizhen, Chen, Man, Wang, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055977/
https://www.ncbi.nlm.nih.gov/pubmed/27738489
http://dx.doi.org/10.1155/2016/1521428