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An outbreak investigation of congenital rubella syndrome in Solomon Islands, 2013

INTRODUCTION: During May 2012, a rubella outbreak was declared in Solomon Islands. A suspected case of congenital rubella syndrome (CRS) was reported from one hospital 11 months later in 2013. This report describes the subsequent CRS investigation, findings and measures implemented. METHODS: Prospec...

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Autores principales: Durski, Kara N, Tituli, Carol, Ogaoga, Divi, Musto, Jennie, Joshua, Cynthia, Dofai, Alfred, Leydon, Jennie, Nilles, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: World Health Organization 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056162/
https://www.ncbi.nlm.nih.gov/pubmed/27757248
http://dx.doi.org/10.5365/WPSAR.2015.6.4.005
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author Durski, Kara N
Tituli, Carol
Ogaoga, Divi
Musto, Jennie
Joshua, Cynthia
Dofai, Alfred
Leydon, Jennie
Nilles, Eric
author_facet Durski, Kara N
Tituli, Carol
Ogaoga, Divi
Musto, Jennie
Joshua, Cynthia
Dofai, Alfred
Leydon, Jennie
Nilles, Eric
author_sort Durski, Kara N
collection PubMed
description INTRODUCTION: During May 2012, a rubella outbreak was declared in Solomon Islands. A suspected case of congenital rubella syndrome (CRS) was reported from one hospital 11 months later in 2013. This report describes the subsequent CRS investigation, findings and measures implemented. METHODS: Prospective CRS surveillance was conducted at the newborn nursery, paediatric and post-natal wards, and the paediatric cardiology and ophthalmology clinics of the study hospital from April to July 2013. Retrospective case finding by reviewing medical records was also undertaken to identify additional cases born between January and March 2013 for the same wards and clinics. Cases were identified using established World Health Organization case definitions for CRS. RESULTS: A total of 13 CRS cases were identified, including two laboratory-confirmed, four clinically confirmed and seven suspected cases. Five CRS cases were retrospectively identified, including four suspected and one clinically confirmed case. There was no geospatial clustering of residences. The mothers of the cases were aged between 20 and 36 years. Three of the six mothers available for interview recalled an acute illness with rash during the first trimester of pregnancy. DISCUSSION: Additional CRS cases not captured in this investigation are likely. Caring for CRS cases is a challenge in resource-poor settings. Rubella vaccination is safe and effective and can prevent the serious consequences of CRS. Well planned and funded vaccination activities can prevent future CRS cases.
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spelling pubmed-50561622016-10-18 An outbreak investigation of congenital rubella syndrome in Solomon Islands, 2013 Durski, Kara N Tituli, Carol Ogaoga, Divi Musto, Jennie Joshua, Cynthia Dofai, Alfred Leydon, Jennie Nilles, Eric Western Pac Surveill Response J Outbreak Investigation Report INTRODUCTION: During May 2012, a rubella outbreak was declared in Solomon Islands. A suspected case of congenital rubella syndrome (CRS) was reported from one hospital 11 months later in 2013. This report describes the subsequent CRS investigation, findings and measures implemented. METHODS: Prospective CRS surveillance was conducted at the newborn nursery, paediatric and post-natal wards, and the paediatric cardiology and ophthalmology clinics of the study hospital from April to July 2013. Retrospective case finding by reviewing medical records was also undertaken to identify additional cases born between January and March 2013 for the same wards and clinics. Cases were identified using established World Health Organization case definitions for CRS. RESULTS: A total of 13 CRS cases were identified, including two laboratory-confirmed, four clinically confirmed and seven suspected cases. Five CRS cases were retrospectively identified, including four suspected and one clinically confirmed case. There was no geospatial clustering of residences. The mothers of the cases were aged between 20 and 36 years. Three of the six mothers available for interview recalled an acute illness with rash during the first trimester of pregnancy. DISCUSSION: Additional CRS cases not captured in this investigation are likely. Caring for CRS cases is a challenge in resource-poor settings. Rubella vaccination is safe and effective and can prevent the serious consequences of CRS. Well planned and funded vaccination activities can prevent future CRS cases. World Health Organization 2016-02-03 /pmc/articles/PMC5056162/ /pubmed/27757248 http://dx.doi.org/10.5365/WPSAR.2015.6.4.005 Text en (c) 2016 The authors; licensee World Health Organization. This is an open access article distributed under the terms of the Creative Commons Attribution IGO License (http://creativecommons.org/licenses/by/3.0/igo/legalcode), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. In any reproduction of this article there should not be any suggestion that WHO or this article endorse any specific organization or products. The use of the WHO logo is not permitted. This notice should be preserved along with the article's original URL.
spellingShingle Outbreak Investigation Report
Durski, Kara N
Tituli, Carol
Ogaoga, Divi
Musto, Jennie
Joshua, Cynthia
Dofai, Alfred
Leydon, Jennie
Nilles, Eric
An outbreak investigation of congenital rubella syndrome in Solomon Islands, 2013
title An outbreak investigation of congenital rubella syndrome in Solomon Islands, 2013
title_full An outbreak investigation of congenital rubella syndrome in Solomon Islands, 2013
title_fullStr An outbreak investigation of congenital rubella syndrome in Solomon Islands, 2013
title_full_unstemmed An outbreak investigation of congenital rubella syndrome in Solomon Islands, 2013
title_short An outbreak investigation of congenital rubella syndrome in Solomon Islands, 2013
title_sort outbreak investigation of congenital rubella syndrome in solomon islands, 2013
topic Outbreak Investigation Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056162/
https://www.ncbi.nlm.nih.gov/pubmed/27757248
http://dx.doi.org/10.5365/WPSAR.2015.6.4.005
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