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mTORC1-Activated Monocytes Increase Tregs and Inhibit the Immune Response to Bacterial Infections

The TSC1/2 heterodimer, a key upstream regulator of the mTOR, can inhibit the activation of mTOR, which plays a critical role in immune responses after bacterial infections. Monocytes are an innate immune cell type that have been shown to be involved in bacteremia. However, how the mTOR pathway is i...

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Detalles Bibliográficos
Autores principales:	Fang, Lijun, Tu, Huaijun, Guo, Wei, Wang, Shixuan, Xue, Ting, Yang, Fei, Zhang, Xiaoyan, Yang, Yazhi, Wan, Qian, Shi, Zhexin, Zhan, Xulong, Li, Jian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056273/ https://www.ncbi.nlm.nih.gov/pubmed/27746591 http://dx.doi.org/10.1155/2016/7369351

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