Coordinated Upregulation of Mitochondrial Biogenesis and Autophagy in Breast Cancer Cells: The Role of Dynamin Related Protein-1 and Implication for Breast Cancer Treatment

Overactive mitochondrial fission was shown to promote cell transformation and tumor growth. It remains elusive how mitochondrial quality is regulated in such conditions. Here, we show that upregulation of mitochondrial fission protein, dynamin related protein-1 (Drp1), was accompanied with increased...

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Detalles Bibliográficos
Autores principales: Zou, Peng, Liu, Longhua, Zheng, Louise D., Payne, Kyle K., Manjili, Masoud H., Idowu, Michael O., Zhang, Jinfeng, Schmelz, Eva M., Cheng, Zhiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056295/
https://www.ncbi.nlm.nih.gov/pubmed/27746856
http://dx.doi.org/10.1155/2016/4085727

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