Oncogenic fingerprint of epidermal growth factor receptor pathway and emerging epidermal growth factor receptor blockade resistance in colorectal cancer

Epidermal growth factor receptor (EGFR) has been an attractive target for treatment of epithelial cancers, including colorectal cancer (CRC). Evidence from clinical trials indicates that cetuximab and panitumumab (anti-EGFR monoclonal antibodies) have clinical activity in patients with metastatic CR...

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Detalles Bibliográficos
Autores principales: Sobani, Zain A, Sawant, Ashwin, Jafri, Mikram, Correa, Amit Keith, Sahin, Ibrahim Halil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056326/
https://www.ncbi.nlm.nih.gov/pubmed/27777877
http://dx.doi.org/10.5306/wjco.v7.i5.340

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