Neurodevelopmental Expression Profile of Dimeric and Monomeric Group 1 mGluRs: Relevance to Schizophrenia Pathogenesis and Treatment

Group 1 metabotropic glutamate receptors (mGluR1/mGluR5) play an integral role in neurodevelopment and are implicated in psychiatric disorders, such as schizophrenia. mGluR1 and mGluR5 are expressed as homodimers, which is important for their functionality and pharmacology. We examined the protein e...

Descripción completa

Detalles Bibliográficos
Autores principales: Lum, Jeremy S., Fernandez, Francesca, Matosin, Natalie, Andrews, Jessica L., Huang, Xu-Feng, Ooi, Lezanne, Newell, Kelly A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056358/
https://www.ncbi.nlm.nih.gov/pubmed/27721389
http://dx.doi.org/10.1038/srep34391

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056358/
https://www.ncbi.nlm.nih.gov/pubmed/27721389
http://dx.doi.org/10.1038/srep34391

Ejemplares similares