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Autonomously folded α-helical lockers promote RNAi*

RNAi is an indispensable research tool with a substantial therapeutic potential. However, the complete transition of the approach to an applied capability remains hampered due to poorly understood relationships between siRNA delivery and gene suppression. Here we propose that interfacial tertiary co...

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Detalles Bibliográficos
Autores principales: Guyader, Christian P. E., Lamarre, Baptiste, De Santis, Emiliana, Noble, James E., Slater, Nigel K., Ryadnov, Maxim G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056365/
https://www.ncbi.nlm.nih.gov/pubmed/27721465
http://dx.doi.org/10.1038/srep35012

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