Cargando…
Autonomously folded α-helical lockers promote RNAi*
RNAi is an indispensable research tool with a substantial therapeutic potential. However, the complete transition of the approach to an applied capability remains hampered due to poorly understood relationships between siRNA delivery and gene suppression. Here we propose that interfacial tertiary co...
Autores principales: | Guyader, Christian P. E., Lamarre, Baptiste, De Santis, Emiliana, Noble, James E., Slater, Nigel K., Ryadnov, Maxim G. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056365/ https://www.ncbi.nlm.nih.gov/pubmed/27721465 http://dx.doi.org/10.1038/srep35012 |
Ejemplares similares
-
Modulating charge-dependent and folding-mediated antimicrobial interactions at peptide–lipid interfaces
por: Iavicoli, Patrizia, et al.
Publicado: (2016) -
Structurally plastic peptide capsules for synthetic antimicrobial viruses
por: Castelletto, Valeria, et al.
Publicado: (2016) -
Lockers
Publicado: (1893) -
Antimicrobial peptide capsids of de novo design
por: De Santis, Emiliana, et al.
Publicado: (2017) -
To Fold or
Not to Fold: Diastereomeric Optimization
of an α-Helical Antimicrobial Peptide
por: Personne, Hippolyte, et al.
Publicado: (2023)