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p21(Cip1) plays a critical role in the physiological adaptation to fasting through activation of PPARα
Fasting is a physiological stress that elicits well-known metabolic adaptations, however, little is known about the role of stress-responsive tumor suppressors in fasting. Here, we have examined the expression of several tumor suppressors upon fasting in mice. Interestingly, p21 mRNA is uniquely ind...
Autores principales: | Lopez-Guadamillas, Elena, Fernandez-Marcos, Pablo J., Pantoja, Cristina, Muñoz-Martin, Maribel, Martínez, Dolores, Gómez-López, Gonzalo, Campos-Olivas, Ramón, Valverde, Angela M., Serrano, Manuel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056372/ https://www.ncbi.nlm.nih.gov/pubmed/27721423 http://dx.doi.org/10.1038/srep34542 |
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