Oleoylethanolamide exerts anti-inflammatory effects on LPS-induced THP-1 cells by enhancing PPARα signaling and inhibiting the NF-κB and ERK1/2/AP-1/STAT3 pathways

The present study aimed to examine the anti-inflammatory actions of oleoylethanolamide (OEA) in lipopolysaccharide (LPS)-induced THP-1 cells. The cells were stimulated with LPS (1 μg/ml) in the presence or absence of OEA (10, 20 and 40 μM). The pro-inflammatory cytokines were evaluated by qRT-PCR an...

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Detalles Bibliográficos
Autores principales: Yang, Lichao, Guo, Han, Li, Ying, Meng, Xianglan, Yan, Lu, Dan Zhang, Wu, Sangang, Zhou, Hao, Peng, Lu, Xie, Qiang, Jin, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056375/
https://www.ncbi.nlm.nih.gov/pubmed/27721381
http://dx.doi.org/10.1038/srep34611

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056375/
https://www.ncbi.nlm.nih.gov/pubmed/27721381
http://dx.doi.org/10.1038/srep34611

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