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Redefining the BH3 Death Domain as a ‘Short Linear Motif’

B cell lymphoma-2 (BCL-2)-related proteins control programmed cell death through a complex network of protein–protein interactions mediated by BCL-2 homology 3 (BH3) domains. Given their roles as dynamic linchpins, the discovery of novel BH3-containing proteins has attracted considerable attention....

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Detalles Bibliográficos
Autores principales: Aouacheria, Abdel, Combet, Christophe, Tompa, Peter, Hardwick, J. Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056427/
https://www.ncbi.nlm.nih.gov/pubmed/26541461
http://dx.doi.org/10.1016/j.tibs.2015.09.007