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Lateral opening in the intact β-barrel assembly machinery captured by cryo-EM

The β-barrel assembly machinery (BAM) is a ∼203 kDa complex of five proteins (BamA–E), which is essential for viability in E. coli. BAM promotes the folding and insertion of β-barrel proteins into the outer membrane via a poorly understood mechanism. Several current models suggest that BAM functions...

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Detalles Bibliográficos
Autores principales: Iadanza, Matthew G., Higgins, Anna J., Schiffrin, Bob, Calabrese, Antonio N., Brockwell, David J., Ashcroft, Alison E., Radford, Sheena E., Ranson, Neil A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056442/
https://www.ncbi.nlm.nih.gov/pubmed/27686148
http://dx.doi.org/10.1038/ncomms12865