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Characterization of left and right atrial function in healthy volunteers by cardiovascular magnetic resonance

BACKGROUND: Left and right atrial function show a different pattern in advanced age in order to maintain adequate ventricular filling. It has been shown that left atrial (LA) function has a prognostic value in a number of heart conditions. Cardiovascular magnetic resonance (CMR) provides high qualit...

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Autores principales: Maceira, Alicia M., Cosin-Sales, Juan, Prasad, Sanjay K., Pennell, Dudley J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056480/
https://www.ncbi.nlm.nih.gov/pubmed/27719670
http://dx.doi.org/10.1186/s12968-016-0284-8
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author Maceira, Alicia M.
Cosin-Sales, Juan
Prasad, Sanjay K.
Pennell, Dudley J.
author_facet Maceira, Alicia M.
Cosin-Sales, Juan
Prasad, Sanjay K.
Pennell, Dudley J.
author_sort Maceira, Alicia M.
collection PubMed
description BACKGROUND: Left and right atrial function show a different pattern in advanced age in order to maintain adequate ventricular filling. It has been shown that left atrial (LA) function has a prognostic value in a number of heart conditions. Cardiovascular magnetic resonance (CMR) provides high quality images of the left and right atria using high temporal resolution steady state free precession (SSFP) cine sequences. We used SSFP cines to characterize atrial function in healthy, normotensive, volunteers. METHODS: We measured maximum, preatrial contraction and minimum left and right atrial volumes in 120 healthy subjects after careful exclusion of cardiovascular abnormality (60 men, 60 women; 20 subjects per age decile from 20 to 80 years). Data were generated from 3-dimensional modeling, including tracking of the atrioventricular ring motion and time-volume curves analysis. With those measurements, all the usual parameters for left and right atrial function were calculated. RESULTS: Gender had significant influence on some parameters of left and right atrial conduit and booster pump function. Age significantly influenced the majority of parameters of both left and right atrial function, with typically lower reservoir and conduit functions and higher booster pump function, both in males and females belonging to older age groups. CMR normal ranges were modelled for clinical use with normalization, where appropriate, for body surface area and gender, displaying parameters with respect to age. CONCLUSIONS: CMR normal reference ranges for components of left and right atrial function are provided for males and females for a wide age range.
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spelling pubmed-50564802016-10-20 Characterization of left and right atrial function in healthy volunteers by cardiovascular magnetic resonance Maceira, Alicia M. Cosin-Sales, Juan Prasad, Sanjay K. Pennell, Dudley J. J Cardiovasc Magn Reson Research BACKGROUND: Left and right atrial function show a different pattern in advanced age in order to maintain adequate ventricular filling. It has been shown that left atrial (LA) function has a prognostic value in a number of heart conditions. Cardiovascular magnetic resonance (CMR) provides high quality images of the left and right atria using high temporal resolution steady state free precession (SSFP) cine sequences. We used SSFP cines to characterize atrial function in healthy, normotensive, volunteers. METHODS: We measured maximum, preatrial contraction and minimum left and right atrial volumes in 120 healthy subjects after careful exclusion of cardiovascular abnormality (60 men, 60 women; 20 subjects per age decile from 20 to 80 years). Data were generated from 3-dimensional modeling, including tracking of the atrioventricular ring motion and time-volume curves analysis. With those measurements, all the usual parameters for left and right atrial function were calculated. RESULTS: Gender had significant influence on some parameters of left and right atrial conduit and booster pump function. Age significantly influenced the majority of parameters of both left and right atrial function, with typically lower reservoir and conduit functions and higher booster pump function, both in males and females belonging to older age groups. CMR normal ranges were modelled for clinical use with normalization, where appropriate, for body surface area and gender, displaying parameters with respect to age. CONCLUSIONS: CMR normal reference ranges for components of left and right atrial function are provided for males and females for a wide age range. BioMed Central 2016-10-10 /pmc/articles/PMC5056480/ /pubmed/27719670 http://dx.doi.org/10.1186/s12968-016-0284-8 Text en © The Author(s). 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research
Maceira, Alicia M.
Cosin-Sales, Juan
Prasad, Sanjay K.
Pennell, Dudley J.
Characterization of left and right atrial function in healthy volunteers by cardiovascular magnetic resonance
title Characterization of left and right atrial function in healthy volunteers by cardiovascular magnetic resonance
title_full Characterization of left and right atrial function in healthy volunteers by cardiovascular magnetic resonance
title_fullStr Characterization of left and right atrial function in healthy volunteers by cardiovascular magnetic resonance
title_full_unstemmed Characterization of left and right atrial function in healthy volunteers by cardiovascular magnetic resonance
title_short Characterization of left and right atrial function in healthy volunteers by cardiovascular magnetic resonance
title_sort characterization of left and right atrial function in healthy volunteers by cardiovascular magnetic resonance
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056480/
https://www.ncbi.nlm.nih.gov/pubmed/27719670
http://dx.doi.org/10.1186/s12968-016-0284-8
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