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Anti-thrombotic agents derived from snake venom proteins

Snake venoms affect blood coagulation and platelet function in a complex manner. However, two classes of venom proteins, snaclecs and disintegrins have been shown to specifically target receptors including GPIb, α2β1, GPVI, CLEC-2 and integrins αIIbβ3, αvβ3, α5β1 expressed on platelets, endothelial...

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Detalles Bibliográficos
Autores principales: Huang, Tur-Fu, Hsu, Chun-Chieh, Kuo, Yu-Ju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056499/
https://www.ncbi.nlm.nih.gov/pubmed/27766044
http://dx.doi.org/10.1186/s12959-016-0113-1

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