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Anti-thrombotic agents derived from snake venom proteins
Snake venoms affect blood coagulation and platelet function in a complex manner. However, two classes of venom proteins, snaclecs and disintegrins have been shown to specifically target receptors including GPIb, α2β1, GPVI, CLEC-2 and integrins αIIbβ3, αvβ3, α5β1 expressed on platelets, endothelial...
Autores principales: | Huang, Tur-Fu, Hsu, Chun-Chieh, Kuo, Yu-Ju |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056499/ https://www.ncbi.nlm.nih.gov/pubmed/27766044 http://dx.doi.org/10.1186/s12959-016-0113-1 |
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