Dies1/VISTA expression loss is a recurrent event in gastric cancer due to epigenetic regulation

Dies1/VISTA induces embryonic stem-cell differentiation, via BMP-pathway, but also acts as inflammation regulator and immune-response modulator. Dies1 inhibition in a melanoma-mouse model led to increased tumour-infiltrating T-cells and decreased tumour growth, emphasizing Dies1 relevance in tumour-...

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Detalles Bibliográficos
Autores principales: Oliveira, Patrícia, Carvalho, Joana, Rocha, Sara, Azevedo, Mafalda, Reis, Inês, Camilo, Vânia, Sousa, Bárbara, Valente, Sofia, Paredes, Joana, Almeida, Raquel, Huntsman, David, Oliveira, Carla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056517/
https://www.ncbi.nlm.nih.gov/pubmed/27721458
http://dx.doi.org/10.1038/srep34860

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056517/
https://www.ncbi.nlm.nih.gov/pubmed/27721458
http://dx.doi.org/10.1038/srep34860

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