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Evaluating Transcription Factor Activity Changes by Scoring Unexplained Target Genes in Expression Data

Several methods predict activity changes of transcription factors (TFs) from a given regulatory network and measured expression data. But available gene regulatory networks are incomplete and contain many condition-dependent regulations that are not relevant for the specific expression measurement....

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Detalles Bibliográficos
Autores principales: Berchtold, Evi, Csaba, Gergely, Zimmer, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056719/
https://www.ncbi.nlm.nih.gov/pubmed/27723775
http://dx.doi.org/10.1371/journal.pone.0164513