ATM function and its relationship with ATM gene mutations in chronic lymphocytic leukemia with the recurrent deletion (11q22.3-23.2)

Approximately 10–20% of chronic lymphocytic leukemia (CLL) patients exhibit del(11q22–23) before treatment, this cohort increases to over 40% upon progression following chemoimmunotherapy. The coding sequence of the DNA damage response gene, ataxia-telangiectasia-mutated (ATM), is contained in this...

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Detalles Bibliográficos
Autores principales: Jiang, Y, Chen, H-C, Su, X, Thompson, P A, Liu, X, Do, K-A, Wierda, W, Keating, M J, Plunkett, W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056966/
https://www.ncbi.nlm.nih.gov/pubmed/27588518
http://dx.doi.org/10.1038/bcj.2016.69

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