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Ecdysone Receptor-based Singular Gene Switches for Regulated Transgene Expression in Cells and Adult Rodent Tissues

Controlled gene expression is an indispensable technique in biomedical research. Here, we report a convenient, straightforward, and reliable way to induce expression of a gene of interest with negligible background expression compared to the most widely used tetracycline (Tet)-regulated system. Expl...

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Detalles Bibliográficos
Autores principales: Lee, Seoghyun, Sohn, Kyung-Cheol, Choi, Dae-Kyoung, Won, Minho, Park, Kyeong Ah, Ju, Sung-Kyu, Kang, Kidong, Bae, Young-Ki, Hur, Gang Min, Ro, Hyunju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056996/
https://www.ncbi.nlm.nih.gov/pubmed/27673563
http://dx.doi.org/10.1038/mtna.2016.74