Nuclear envelope rupture: Actin fibers are putting the squeeze on the nucleus

Cells exhibit transient nuclear envelope ruptures during interphase, but the responsible biophysical processes remain unclear. In this issue, Hatch and Hetzer (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201603053) show that actin fibers constrict the nucleus, causing chromatin protrusions and...

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Detalles Bibliográficos
Autores principales: Lammerding, Jan, Wolf, Katarina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5057291/
https://www.ncbi.nlm.nih.gov/pubmed/27697927
http://dx.doi.org/10.1083/jcb.201609102
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author Lammerding, Jan
Wolf, Katarina
author_facet Lammerding, Jan
Wolf, Katarina
author_sort Lammerding, Jan
collection PubMed
description Cells exhibit transient nuclear envelope ruptures during interphase, but the responsible biophysical processes remain unclear. In this issue, Hatch and Hetzer (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201603053) show that actin fibers constrict the nucleus, causing chromatin protrusions and nuclear membrane ruptures at sites with nuclear lamina defects.
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spelling pubmed-50572912017-04-10 Nuclear envelope rupture: Actin fibers are putting the squeeze on the nucleus Lammerding, Jan Wolf, Katarina J Cell Biol Commentary Cells exhibit transient nuclear envelope ruptures during interphase, but the responsible biophysical processes remain unclear. In this issue, Hatch and Hetzer (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201603053) show that actin fibers constrict the nucleus, causing chromatin protrusions and nuclear membrane ruptures at sites with nuclear lamina defects. The Rockefeller University Press 2016-10-10 /pmc/articles/PMC5057291/ /pubmed/27697927 http://dx.doi.org/10.1083/jcb.201609102 Text en © 2016 Lammerding and Wolf This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).
spellingShingle Commentary
Lammerding, Jan
Wolf, Katarina
Nuclear envelope rupture: Actin fibers are putting the squeeze on the nucleus
title Nuclear envelope rupture: Actin fibers are putting the squeeze on the nucleus
title_full Nuclear envelope rupture: Actin fibers are putting the squeeze on the nucleus
title_fullStr Nuclear envelope rupture: Actin fibers are putting the squeeze on the nucleus
title_full_unstemmed Nuclear envelope rupture: Actin fibers are putting the squeeze on the nucleus
title_short Nuclear envelope rupture: Actin fibers are putting the squeeze on the nucleus
title_sort nuclear envelope rupture: actin fibers are putting the squeeze on the nucleus
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5057291/
https://www.ncbi.nlm.nih.gov/pubmed/27697927
http://dx.doi.org/10.1083/jcb.201609102
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