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The Montrachet Study: study design, methodology and analysis of visual acuity and refractive errors in an elderly population

PURPOSE: To describe the design of the Montrachet Study (Maculopathy Optic Nerve nuTRition neurovAsCular and HEarT diseases) and to report visual acuity and refractive errors in this elderly population. METHODS: Participants were recruited in Dijon (France), from the ongoing population‐based 3C Stud...

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Autores principales: Creuzot‐Garcher, Catherine, Binquet, Christine, Daniel, Sandrine, Bretillon, Lionel, Acar, Nyiazi, de Lazzer, Aurélie, Arnould, Laurent, Tzourio, Christophe, Bron, Alain M., Delcourt, Cécile
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5057364/
https://www.ncbi.nlm.nih.gov/pubmed/26466845
http://dx.doi.org/10.1111/aos.12842
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author Creuzot‐Garcher, Catherine
Binquet, Christine
Daniel, Sandrine
Bretillon, Lionel
Acar, Nyiazi
de Lazzer, Aurélie
Arnould, Laurent
Tzourio, Christophe
Bron, Alain M.
Delcourt, Cécile
author_facet Creuzot‐Garcher, Catherine
Binquet, Christine
Daniel, Sandrine
Bretillon, Lionel
Acar, Nyiazi
de Lazzer, Aurélie
Arnould, Laurent
Tzourio, Christophe
Bron, Alain M.
Delcourt, Cécile
author_sort Creuzot‐Garcher, Catherine
collection PubMed
description PURPOSE: To describe the design of the Montrachet Study (Maculopathy Optic Nerve nuTRition neurovAsCular and HEarT diseases) and to report visual acuity and refractive errors in this elderly population. METHODS: Participants were recruited in Dijon (France), from the ongoing population‐based 3C Study. In 2009–2011, 1153 participants from the 3 Cities Study, aged 75 years or more, had an initial eye examination and were scheduled for eye examinations. The eye examination comprised visual acuity, refraction, visual field, ocular surface assessment, photographs and OCT of the macula and the optic disc, measurement of intra‐ocular pressure, central corneal thickness and macular pigment assessment. Information on cardiovascular and neurologic diseases and a large comprehensive database (blood samples, genetic testing, cognitive tests, MRI) were available from the 3C Study. RESULTS: Presenting visual acuity <20/60 in the better eye was found in 2.3% (95% CI 1.5–3.2) of the participants with no gender differences. Visual impairment increased with age from 1.5% (95% CI 0.3–2.7) for those aged 75–79 years to 5.6% (95% CI 2.9–8.4) for patients 85 years and older (p = 0.0003). Spherical equivalent did not differ between men and women (p = 0.8) and decreased with age whatever the lens status. CONCLUSION: Despite the high prevalence of self‐reported eye diseases in this elderly population, visual impairment was low and increased with age. The Montrachet Study may help to better estimate the prevalence of eye diseases in people over 75 years of age and to seek associations with cardiovascular and neurologic diseases and their potential risk factors.
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spelling pubmed-50573642016-10-19 The Montrachet Study: study design, methodology and analysis of visual acuity and refractive errors in an elderly population Creuzot‐Garcher, Catherine Binquet, Christine Daniel, Sandrine Bretillon, Lionel Acar, Nyiazi de Lazzer, Aurélie Arnould, Laurent Tzourio, Christophe Bron, Alain M. Delcourt, Cécile Acta Ophthalmol Original Articles PURPOSE: To describe the design of the Montrachet Study (Maculopathy Optic Nerve nuTRition neurovAsCular and HEarT diseases) and to report visual acuity and refractive errors in this elderly population. METHODS: Participants were recruited in Dijon (France), from the ongoing population‐based 3C Study. In 2009–2011, 1153 participants from the 3 Cities Study, aged 75 years or more, had an initial eye examination and were scheduled for eye examinations. The eye examination comprised visual acuity, refraction, visual field, ocular surface assessment, photographs and OCT of the macula and the optic disc, measurement of intra‐ocular pressure, central corneal thickness and macular pigment assessment. Information on cardiovascular and neurologic diseases and a large comprehensive database (blood samples, genetic testing, cognitive tests, MRI) were available from the 3C Study. RESULTS: Presenting visual acuity <20/60 in the better eye was found in 2.3% (95% CI 1.5–3.2) of the participants with no gender differences. Visual impairment increased with age from 1.5% (95% CI 0.3–2.7) for those aged 75–79 years to 5.6% (95% CI 2.9–8.4) for patients 85 years and older (p = 0.0003). Spherical equivalent did not differ between men and women (p = 0.8) and decreased with age whatever the lens status. CONCLUSION: Despite the high prevalence of self‐reported eye diseases in this elderly population, visual impairment was low and increased with age. The Montrachet Study may help to better estimate the prevalence of eye diseases in people over 75 years of age and to seek associations with cardiovascular and neurologic diseases and their potential risk factors. John Wiley and Sons Inc. 2015-10-15 2016-03 /pmc/articles/PMC5057364/ /pubmed/26466845 http://dx.doi.org/10.1111/aos.12842 Text en © 2015 The Authors. Acta Ophthalmologica published by John Wiley & Sons Ltd on behalf of Acta Ophthalmologica Scandinavica Foundation. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs (http://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Original Articles
Creuzot‐Garcher, Catherine
Binquet, Christine
Daniel, Sandrine
Bretillon, Lionel
Acar, Nyiazi
de Lazzer, Aurélie
Arnould, Laurent
Tzourio, Christophe
Bron, Alain M.
Delcourt, Cécile
The Montrachet Study: study design, methodology and analysis of visual acuity and refractive errors in an elderly population
title The Montrachet Study: study design, methodology and analysis of visual acuity and refractive errors in an elderly population
title_full The Montrachet Study: study design, methodology and analysis of visual acuity and refractive errors in an elderly population
title_fullStr The Montrachet Study: study design, methodology and analysis of visual acuity and refractive errors in an elderly population
title_full_unstemmed The Montrachet Study: study design, methodology and analysis of visual acuity and refractive errors in an elderly population
title_short The Montrachet Study: study design, methodology and analysis of visual acuity and refractive errors in an elderly population
title_sort montrachet study: study design, methodology and analysis of visual acuity and refractive errors in an elderly population
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5057364/
https://www.ncbi.nlm.nih.gov/pubmed/26466845
http://dx.doi.org/10.1111/aos.12842
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