Aldehyde dehydrogenase activity plays a Key role in the aggressive phenotype of neuroblastoma

BACKGROUND: The successful targeting of neuroblastoma (NB) by associating tumor-initiating cells (TICs) is a major challenge in the development of new therapeutic strategies. The subfamily of aldehyde dehydrogenases 1 (ALDH1) isoenzymes, which comprises ALDH1A1, ALDH1A2, and ALDH1A3, is involved in...

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Detalles Bibliográficos
Autores principales: Flahaut, Marjorie, Jauquier, Nicolas, Chevalier, Nadja, Nardou, Katya, Balmas Bourloud, Katia, Joseph, Jean-Marc, Barras, David, Widmann, Christian, Gross, Nicole, Renella, Raffaele, Mühlethaler-Mottet, Annick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5057398/
https://www.ncbi.nlm.nih.gov/pubmed/27724856
http://dx.doi.org/10.1186/s12885-016-2820-1

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