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TP53 gene mutation analysis in chronic lymphocytic leukemia by nanopore MinION sequencing
BACKGROUND: The assessment of TP53 mutational status is becoming a routine clinical practice for chronic lymphocytic leukemia patients (CLL). A broad spectrum of molecular techniques has been employed so far, including both direct Sanger sequencing and next generation sequencing. Oxford Nanopore Tec...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5057401/ https://www.ncbi.nlm.nih.gov/pubmed/27724982 http://dx.doi.org/10.1186/s13000-016-0550-y |