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RhoA/rock signaling mediates peroxynitrite-induced functional impairment of Rat coronary vessels

BACKGROUND: Diabetes-induced vascular dysfunction may arise from reduced nitric oxide (NO) availability, following interaction with superoxide to form peroxynitrite. Peroxynitrite can induce formation of 3-nitrotyrosine-modified proteins. RhoA/ROCK signaling is also involved in diabetes-induced vasc...

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Detalles Bibliográficos
Autores principales:	Sun, Zhijun, Wu, Xing, Li, Weiping, Peng, Hui, Shen, Xuhua, Ma, Lu, Liu, Huirong, Li, Hongwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5057502/ https://www.ncbi.nlm.nih.gov/pubmed/27724862 http://dx.doi.org/10.1186/s12872-016-0372-6

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