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The Biophysical Characterisation and SAXS Analysis of Human NLRP1 Uncover a New Level of Complexity of NLR Proteins

NOD-like receptors represent an important class of germline-encoded pattern recognition receptors that play key roles in the regulation of inflammatory signalling pathways. They function as danger sensors and initiate inflammatory responses and the production of cytokines. Since NLR malfunction resu...

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Detalles Bibliográficos
Autores principales: Martino, Luigi, Holland, Louise, Christodoulou, Evangelos, Kunzelmann, Simone, Esposito, Diego, Rittinger, Katrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5058472/
https://www.ncbi.nlm.nih.gov/pubmed/27727326
http://dx.doi.org/10.1371/journal.pone.0164662

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