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The Biophysical Characterisation and SAXS Analysis of Human NLRP1 Uncover a New Level of Complexity of NLR Proteins
NOD-like receptors represent an important class of germline-encoded pattern recognition receptors that play key roles in the regulation of inflammatory signalling pathways. They function as danger sensors and initiate inflammatory responses and the production of cytokines. Since NLR malfunction resu...
Autores principales: | Martino, Luigi, Holland, Louise, Christodoulou, Evangelos, Kunzelmann, Simone, Esposito, Diego, Rittinger, Katrin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5058472/ https://www.ncbi.nlm.nih.gov/pubmed/27727326 http://dx.doi.org/10.1371/journal.pone.0164662 |
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