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Crosstalk between insulin-like growth factor-1 and angiotensin-II in dopaminergic neurons and glial cells: role in neuroinflammation and aging
The local renin-angiotensin system (RAS) and insulin-like growth factor 1 (IGF-1) have been involved in longevity, neurodegeneration and aging-related dopaminergic degeneration. However, it is not known whether IGF-1 and angiotensin-II (AII) activate each other. In the present study, AII, via type 1...
Autores principales: | Rodriguez-Perez, Ana I., Borrajo, Ana, Diaz-Ruiz, Carmen, Garrido-Gil, Pablo, Labandeira-Garcia, Jose L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5058663/ https://www.ncbi.nlm.nih.gov/pubmed/27167199 http://dx.doi.org/10.18632/oncotarget.9174 |
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