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SOX9 indirectly regulates CEACAM1 expression and immune resistance in melanoma cells
As melanoma cells are immunogenic, they instigate an adaptive immune response and production of anti-tumor T-cells. A central factor in this interaction is CEACAM1 (carcinoembryonic antigen cell adhesion molecule 1), a transmembrane glycoprotein previously shown in our lab to protect melanoma cells...
Autores principales: | Ashkenazi, Shira, Ortenberg, Rona, Besser, Michal, Schachter, Jacob, Markel, Gal |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5058672/ https://www.ncbi.nlm.nih.gov/pubmed/26885752 http://dx.doi.org/10.18632/oncotarget.7379 |
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