Intratumoral KIT mutational heterogeneity and recurrent KIT/ PDGFRA mutations in KIT/PDGFRA wild-type gastrointestinal stromal tumors

OBJECTIVE: Gastrointestinal stromal tumors (GISTs) with no mutations in exons 9, 11, 13, and 17 of the KIT gene and exons 12, and 18 of the PDGFRA gene were defined as KIT/PDGFRA wild-type and they accounted for ~15–20% of GISTs. However, some KIT/PDGFRA wild-type GISTs with KIT mutations in other e...

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Detalles Bibliográficos
Autores principales: Gao, Jing, Li, Jian, Li, Yanyan, Li, Zhongwu, Gong, Jifang, Wu, Jian, Liu, Na, Dong, Bin, Qi, Changsong, Li, Jie, Shen, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5058677/
https://www.ncbi.nlm.nih.gov/pubmed/26848617
http://dx.doi.org/10.18632/oncotarget.7148

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5058677/
https://www.ncbi.nlm.nih.gov/pubmed/26848617
http://dx.doi.org/10.18632/oncotarget.7148

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