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SUMOylation of HP1α supports association with ncRNA to define responsiveness of breast cancer cells to chemotherapy
Epigenetic reprogramming allows cancer cells to bypass normal checkpoints and potentiate aberrant proliferation. Several chromatin regulators are subject to reversible SUMO-modification but little is known about how SUMOylation of chromatin-remodelers modulates the cancer epigenome. Recently, we dem...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5058684/ https://www.ncbi.nlm.nih.gov/pubmed/27107417 http://dx.doi.org/10.18632/oncotarget.8733 |