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SUMOylation of HP1α supports association with ncRNA to define responsiveness of breast cancer cells to chemotherapy

Epigenetic reprogramming allows cancer cells to bypass normal checkpoints and potentiate aberrant proliferation. Several chromatin regulators are subject to reversible SUMO-modification but little is known about how SUMOylation of chromatin-remodelers modulates the cancer epigenome. Recently, we dem...

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Detalles Bibliográficos
Autores principales: Lin, Feng-Ming, Kumar, Santosh, Ren, Jing, Karami, Samaneh, Bahnassy, Shaymaa, Li, Yue, Zheng, Xiaofeng, Wang, Jing, Bawa-Khalfe, Tasneem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5058684/
https://www.ncbi.nlm.nih.gov/pubmed/27107417
http://dx.doi.org/10.18632/oncotarget.8733