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Twist1 induces distinct cell states depending on TGFBR1-activation

Basic helix-loop-helix transcription factor Twist1 is a master regulator of Epithelial-Mesenchymal Transition (EMT), a cellular program implicated in different stages of development as well as metastatic dissemination of carcinomas. Here, we show that Twist1 requires TGF-beta type-I receptor (TGFBR1...

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Detalles Bibliográficos
Autores principales: Dragoi, Diana, Krattenmacher, Anja, Mishra, Vivek K., Schmidt, Johanna M., Kloos, Uwe J., Meixner, Lisa K., Hauck, Stefanie M., Buggenthin, Felix, Schwartz, Dennis, Marr, Carsten, Johnsen, Steven A., Scheel, Christina H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5058688/
https://www.ncbi.nlm.nih.gov/pubmed/27105506
http://dx.doi.org/10.18632/oncotarget.8878