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Inflammasome-independent role of NLRP12 in suppressing colonic inflammation regulated by Blimp-1

NLRP12 is a member of the Nod-like receptor (NLR). Previous studies have reported enhanced colitis-associated inflammatory responses in NLRP12-deficient mice. In this study, we sought to investigate the role of NLRP12 in DSS-stimulated proinflammatory response in dendritic cells and mice colitis, an...

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Detalles Bibliográficos
Autores principales: Shi, Fushan, Yang, Yang, Kouadir, Mohammed, Xu, Wei, Hu, Songhua, Wang, Tiancheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5058702/
https://www.ncbi.nlm.nih.gov/pubmed/27105524
http://dx.doi.org/10.18632/oncotarget.8872