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A Toll-like receptor 2 agonist-fused antigen enhanced antitumor immunity by increasing antigen presentation and the CD8 memory T cells population
The induction of long-lived effector CD8(+) T cells is key to the development of efficient cancer vaccines. In this study, we demonstrated that a Toll-like receptor 2 (TLR2) agonist-fused antigen increased antigen presentation via TLR2 signaling and induced effector memory-like CD8(+) T cells agains...
Autores principales: | Wu, Chiao-Chieh, Liu, Shih-Jen, Chen, Hsin-Wei, Shen, Kuan-Yin, Leng, Chih-Hsiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5058719/ https://www.ncbi.nlm.nih.gov/pubmed/27127171 http://dx.doi.org/10.18632/oncotarget.9001 |
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