Cargando…

N-acetylcysteine negatively regulates Notch3 and its malignant signaling

Notch3 receptor is expressed in a variety of cancers and the excised active intracellular domain (N3ICD) initiates its signaling cascade. N-acetylcysteine (NAC) as an antioxidant has been implicated in cancer prevention and therapy. In this study, we demonstrated a negative regulation of Notch3 by N...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Xiong, Wang, Ya-Nan, Zhu, Juan-Juan, Liu, Xue-Xia, You, Hui, Gong, Mei-Ying, Zou, Ming, Cheng, Wen-Hsing, Zhu, Jian-Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5058723/ https://www.ncbi.nlm.nih.gov/pubmed/27102435 http://dx.doi.org/10.18632/oncotarget.8806

Ejemplares similares

N-acetylcysteine decreases malignant characteristics of glioblastoma cells by inhibiting Notch2 signaling
por: Deng, Jie, et al.
Publicado: (2019)

Compatibility and aerosol characteristics of beclomethasone mixed with N-acetylcysteine
por: Wu, Xiufeng, et al.
Publicado: (2023)

Possible Beneficial Effects of N-Acetylcysteine for Treatment of Triple-Negative Breast Cancer
por: Kwon, Youngjoo
Publicado: (2021)

N-acetylcysteine in the Treatment of Trichotillomania
por: Rodrigues-Barata, Ana Rita, et al.
Publicado: (2012)

N-acetylcystein in dengue hepatitis
por: Wiwanitkit, Viroj
Publicado: (2014)

Protonation Equilibria of N-Acetylcysteine
por: Fazary, Ahmed E., et al.
Publicado: (2020)

GSH rescue by N-acetylcysteine
por: Ruffmann, R., et al.
Publicado: (1991)

Redox-sensitive MAPK and Notch3 regulate fibroblast differentiation and activation: a dual role of ERK1/2
por: Lai, Jun-Mei, et al.
Publicado: (2016)

Comparison between theophylline, N-acetylcysteine, and theophylline plus N-acetylcysteine for the prevention of contrast-induced nephropathy
por: Arabmomeni, Morteza, et al.
Publicado: (2015)

N-acetylcysteine as an antidote in methylmercury poisoning.
por: Ballatori, N, et al.
Publicado: (1998)

Role of N-acetylcysteine in the management of COPD
por: Sadowska, Anna M, et al.
Publicado: (2006)

The role for N-acetylcysteine in the management of COPD
por: Dekhuijzen, PNR, et al.
Publicado: (2006)

Medical and Dietary Uses of N-Acetylcysteine
por: Šalamon, Špela, et al.
Publicado: (2019)

N-acetylcysteine as an adjunct treatment of schizophrenia
por: Freitas, R. Mota, et al.
Publicado: (2021)

N-Acetylcysteine Regenerates In Vivo Mercaptoalbumin
por: Altomare, Alessandra Anna, et al.
Publicado: (2022)

N-Acetylcysteine Enhances the Recovery of Ischemic Limb in Type-2 Diabetic Mice
por: Zhu, Qiang, et al.
Publicado: (2022)

Oral N-acetylcysteine for prophylaxis of contrast-induced nephropathy in patients following coronary angioplasty: A meta-analysis
por: Li, Jing-Xiu, et al.
Publicado: (2017)

Protective Effects of N-Acetylcysteine in Concanavalin A-Induced Hepatitis in Mice
por: Wang, Chengfen, et al.
Publicado: (2015)

Protective effect of N-acetylcysteine on acute lung injury in septic rats by inhibiting inflammation, oxidation, and apoptosis
por: Le, Jian-wei, et al.
Publicado: (2022)

Methotrexate Promotes Platelet Apoptosis via JNK-Mediated Mitochondrial Damage: Alleviation by N-Acetylcysteine and N-Acetylcysteine Amide
por: Paul, Manoj, et al.
Publicado: (2015)

Activity of N-Acetylcysteine Alone and in Combination with Colistin against Pseudomonas aeruginosa Biofilms and Transcriptomic Response to N-Acetylcysteine Exposure
por: Valzano, Felice, et al.
Publicado: (2022)

Notch3 Interactome Analysis Identified WWP2 as a Negative Regulator of Notch3 Signaling in Ovarian Cancer
por: Jung, Jin-Gyoung, et al.
Publicado: (2014)

N-acetylcysteine attenuates myocardial dysfunction and postischemic injury by restoring caveolin-3/eNOS signaling in diabetic rats
por: Su, Wating, et al.
Publicado: (2016)

N-acetylcysteine protects against cadmium-induced oxidative stress in rat hepatocytes
por: Wang, Jicang, et al.
Publicado: (2014)

N-Acetylcysteine Reverses Cocaine Induced Metaplasticity
por: Moussawi, Khaled, et al.
Publicado: (2009)

Neonatal Gastric Lactobezoar: Management with N-Acetylcysteine
por: Bajorek, Sarah, et al.
Publicado: (2012)

N-acetylcystein in dengue associated severe hepatitis
por: Habaragamuwa, Buddhika Widyaratna Peiris, et al.
Publicado: (2014)

N-acetylcysteine in COPD: why, how, and when?
por: Sanguinetti, Claudio M.
Publicado: (2016)

Treatment of a Gastric Lactobezoar with N-Acetylcysteine
por: Sparks, Brandon, et al.
Publicado: (2014)

N-acetylcysteine overdose after acetaminophen poisoning
por: Mahmoudi, Ghafar Ali, et al.
Publicado: (2015)

Overview on the Effects of N-Acetylcysteine in Neurodegenerative Diseases
por: Tardiolo, Giuseppe, et al.
Publicado: (2018)

N-Acetylcysteine (NAC): Impacts on Human Health
por: Tenório, Micaely Cristina dos Santos, et al.
Publicado: (2021)

N-acetylcysteine in the Treatment of Internet Gaming Disorder
por: Singh, Aakanksha, et al.
Publicado: (2022)

Principles behind SLE treatment with N-acetylcysteine
por: Nasr, Sandy, et al.
Publicado: (2022)

N-acetylcysteine (NAC) and in psychodermatological conditions. Is it useful?
por: Jimenez, A., et al.
Publicado: (2023)

Efficacy and Safety of N-Acetylcysteine for Chronic Obstructive Pulmonary Disease and Chronic Bronchitis
por: Zhang, Li, et al.
Publicado: (2022)

N-Acetylcysteine Reduces Markers of Differentiation in 3T3-L1 Adipocytes
por: Calzadilla, Pablo, et al.
Publicado: (2011)

N-acetylcysteine ameliorates contrast-induced kidney injury in rats with unilateral hydronephrosis
por: Xia, Qiang, et al.
Publicado: (2018)

Negative Regulation of Notch Signaling by Xylose
por: Lee, Tom V., et al.
Publicado: (2013)

N-acetylcysteine attenuates the incidence of phlebitis induced by carbomer/vinorelbine gel
por: Zhang, Hongyu, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_qtffg6a2t9gn6c84aq3t1bcusl