xCT increases tuberculosis susceptibility by regulating antimicrobial function and inflammation

The physiological functions of macrophage, which plays a central role in the pathogenesis of tuberculosis, depend on its redox state. System xc-, a cystine-glutamate transporter, which consists of xCT and CD98, influences many ROS-dependent pathways by regulating the production of the antioxidant gl...

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Detalles Bibliográficos
Autores principales: Cai, Yi, Yang, Qianting, Liao, Mingfeng, Wang, Hao, Zhang, Chi, Nambi, Subhalaxmi, Wang, Wenfei, Zhang, Mingxia, Wu, Junying, Deng, Guofang, Deng, Qunyi, Liu, Haiying, Zhou, Boping, Jin, Qi, Feng, Carl G, Sassetti, Christopher M, Wang, Fudi, Chen, Xinchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5058734/
https://www.ncbi.nlm.nih.gov/pubmed/27129162
http://dx.doi.org/10.18632/oncotarget.9052

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