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The Arf-like GTPase Arl8b is essential for three-dimensional invasive growth of prostate cancer in vitro and xenograft formation and growth in vivo
Cancer is a multistep process that requires cells to respond appropriately to the tumor microenvironment, both in early proliferative stages and in later invasive disease. Arl8b is a lysosome localized Arf-like GTPase that controls the spatial distribution of lysosomes via recruitment of kinesin mot...
Autores principales: | Dykes, Samantha S., Gray, Alana L., Coleman, David T., Saxena, Madhurima, Stephens, Charles A., Carroll, Jennifer L., Pruitt, Kevin, Cardelli, James A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5058737/ https://www.ncbi.nlm.nih.gov/pubmed/27105540 http://dx.doi.org/10.18632/oncotarget.8832 |
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