Cargando…

EphB6 overexpression and Apc mutation together promote colorectal cancer

The erythropoietin-producing hepatocyte (Eph) family tyrosine kinases play important roles in tumorigenesis and cancer aggression. In this study, we investigated the role of EphB6 in oncogenic transformation of colorectal epithelial cells in vitro and in vivo. EphB6 is upregulated in human colorecta...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xu, Dan, Yuan, Liang, Liu, Xin, Li, Mingqi, Zhang, Fubin, Gu, XinYue, Zhang, Dongwei, Yang, Youlin, Cui, Binbin, Tong, Jinxue, Zhou, Jin, Yu, Zhiwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5058743/ https://www.ncbi.nlm.nih.gov/pubmed/27145271 http://dx.doi.org/10.18632/oncotarget.9080

Ejemplares similares

Low Expression of EphB2, EphB3, and EphB4 in Bladder Cancer: Novel Potential Indicators of Muscular Invasion
por: Lee, Tae Ho, et al.
Publicado: (2021)

Reelin induces EphB activation
por: Bouché, Elisabeth, et al.
Publicado: (2013)

The Roles of EphB2 in Cancer
por: Liu, Wei, et al.
Publicado: (2022)

Evaluation of EphA2 and EphB4 as Targets for Image-Guided Colorectal Cancer Surgery
por: Stammes, Marieke A., et al.
Publicado: (2017)

Overexpression of EphB4 promotes neurogenesis, but inhibits neuroinflammation in mice with acute ischemic stroke
por: Wang, Jin, et al.
Publicado: (2021)

EphB2 mediates social isolation-induced memory forgetting
por: Wu, Xin-Rong, et al.
Publicado: (2020)

Structure of the EphB6 receptor ectodomain
por: Mason, Emilia O., et al.
Publicado: (2021)

The Differential Expression of EphB2 and EphB4 Receptor Kinases in Normal Bladder and in Transitional Cell Carcinoma of the Bladder
por: Li, Xiuqing, et al.
Publicado: (2014)

Long noncoding RNA SNHG14 facilitates colorectal cancer metastasis through targeting EZH2-regulated EPHA7
por: Di, Wu, et al.
Publicado: (2019)

Colorectal cancer-associated mutations impair EphB1 kinase function
por: Kim, Yunyoung, et al.
Publicado: (2023)

EphB4 forward signalling regulates lymphatic valve development
por: Zhang, Gu, et al.
Publicado: (2015)

EphB4 as a therapeutic target in mesothelioma
por: Liu, Ren, et al.
Publicado: (2013)

Neuropsin cleaves EphB2 in the amygdala to control anxiety
por: Attwood, Benjamin, et al.
Publicado: (2011)

EphB2: potential therapeutic target for Alzheimer’s disease
Publicado: (2011)

Preferential Control of Basal Dendritic Protrusions by EphB2
por: Kayser, Matthew S., et al.
Publicado: (2011)

EphB/ephrinB Signaling in Cell Adhesion and Migration
por: Park, Inji, et al.
Publicado: (2015)

Paradoxes of the EphB1 receptor in malignant brain tumors
por: Wei, Wenqiang, et al.
Publicado: (2017)

EphB4/EphrinB2 therapeutics in Rhabdomyosarcoma
por: Randolph, Matthew E., et al.
Publicado: (2017)

Key role for EphB2 receptor in kidney fibrosis
por: Huang, Zhimin, et al.
Publicado: (2021)

Overexpression of EphB2 in hippocampus rescues impaired NMDA receptors trafficking and cognitive dysfunction in Alzheimer model
por: Hu, Rui, et al.
Publicado: (2017)

Differential Roles for EphA and EphB Signaling in Segregation and Patterning of Central Vestibulocochlear Nerve Projections
por: Allen-Sharpley, Michelle R., et al.
Publicado: (2013)

Overexpression of EphB6 and EphrinB2 controls soma spacing of cortical neurons in a mutual inhibitory way
por: He, Chun-Hui, et al.
Publicado: (2023)

Neddylation of EphB1 Regulates Its Activity and Associates with Liver Fibrosis
por: Li, Rongxin, et al.
Publicado: (2023)

The receptor tyrosine kinase EphB4 is overexpressed in ovarian cancer, provides survival signals and predicts poor outcome
por: Kumar, S R, et al.
Publicado: (2007)

The EphB6 receptor is overexpressed in pediatric T cell acute lymphoblastic leukemia and increases its sensitivity to doxorubicin treatment
por: El Zawily, Amr, et al.
Publicado: (2017)

Inhibition of choroidal neovascularization by anti-EphB4 monoclonal antibody
por: SU, DONGFENG, et al.
Publicado: (2013)

EphB4 mediates resistance to antiangiogenic therapy in experimental glioma
por: Uhl, Christian, et al.
Publicado: (2018)

The EphB6 Receptor: Kinase-Dead but Very Much Alive
por: Strozen, Timothy G., et al.
Publicado: (2021)

EphrinB2–EphB4 Signaling in Neurooncological Disease
por: Piffko, Andras, et al.
Publicado: (2022)

Molecular Determinants of EphA2 and EphB2 Antagonism Enable the Design of Ligands with Improved Selectivity
por: Guidetti, Lorenzo, et al.
Publicado: (2023)

M6PR- and EphB4-Rich Exosomes Secreted by Serglycin-Overexpressing Esophageal Cancer Cells Promote Cancer Progression
por: Yan, Dongdong, et al.
Publicado: (2023)

PS201. EphB2 in the medial prefrontal cortex regulates vulnerability to stress
por: Zhang, Ruo-Xi, et al.
Publicado: (2016)

EphB4 monomer inhibits chronic graft vasculopathy in an aortic transplant model
por: Langford, John T., et al.
Publicado: (2023)

Role of EphB2/ephrin-B1 signalling in the development and progression of obesity-associated colorectal cancer
por: Suzuki, Yoshiyuki, et al.
Publicado: (2022)

circMELK promotes glioblastoma multiforme cell tumorigenesis through the miR-593/EphB2 axis
por: Zhou, Fengqi, et al.
Publicado: (2021)

Investigation of the expression of the EphB4 receptor tyrosine kinase in prostate carcinoma
por: Lee, Yen-Ching, et al.
Publicado: (2005)

Multiple EphB receptor tyrosine kinases shape dendritic spines in the hippocampus
por: Henkemeyer, Mark, et al.
Publicado: (2003)

Involvement of EphB1 Receptors Signalling in Models of Inflammatory and Neuropathic Pain
por: Cibert-Goton, Vincent, et al.
Publicado: (2013)

The composition of EphB2 clusters determines the strength in the cellular repulsion response
por: Schaupp, Andreas, et al.
Publicado: (2014)

Critical roles for EphB and ephrin-B bidirectional signaling in retinocollicular mapping
por: Thakar, Sonal, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_n8l2tq8g2h315f4bhot90fnfph